Paul Turner, Senior Associate

Paul Turner, Senior Associate

Two years after the discovery, OMKO1 was applied to a patient’s aortic graft that had become contaminated with P. aeruginosa . Following a single application, the phage/antibiotic therapy resolved the infection with no signs of recurrence. “There is plenty of energy in addressing basic questions in biology using the smallest inhabitants of the planet,” says Paul E. Turner, the Rachel Carson Professor of Ecology and Evolutionary Biology at Yale University.

Professor Turner works with colleagues at VECTOR to review the pure history and evolution of pathogenic RNA viruses corresponding to Crimean Congo Hemorrhagic Fever. His non-analysis work focuses on growth of human and laboratory capacity for diagnostic microbiology in low-resource settings. Turner makes a compelling case that viruses are extra biologically successful than cellular life, such as in a 2013 evaluation that he coauthored . The article examines gauges of biological success, including numerical abundance, environmental tolerance, type biodiversity, reproductive potential, and widespread influence on different organisms.

Study At Cambridge

Paul Turner describes the basic biology of viruses, and supplies an introduction to phage therapy, and how it may be improved by applying ‘evolution thinking. Dr. Paul Turner is Professor of Ecology and Evolutionary Biology at Yale University, and holds an appointment within the Microbiology Program at Yale School of Medicine. His laboratory studies how viruses evolutionarily adapt to beat environmental challenges, similar to temperature adjustments or an infection of novel host species. Turner received his bachelor’s degree in Biology from the University of Rochester in 1988, and accomplished his graduate studies in microbial ecology and evolution at Michigan State University in 1995. Turner’s applied research includes looking for pure merchandise that may be useful in combating necessary pathogens.

paul turner

Dr. Turner obtained a Biology diploma from University of Rochester, and Ph.D. in Zoology from Michigan State University. He did postdoctoral coaching at National Institutes of Health, University of Valencia in Spain, and University of Maryland-College Park, before becoming a member of Yale’s Ecology and Evolutionary Biology Department in 2001. He chaired the Watkins Graduate Research Fellowship award committee for ASM, and received the E.E. Just Endowed Research Fellowship and William Townsend Porter Award from Marine Biological Laboratory, and fellowships from Woodrow Wilson Foundation, NSF, NIH and HHMI. Dr. Turner has served as Director of Graduate Studies and as Chair of the Ecology and Evolutionary Biology Department at Yale, as well as Yale’s Dean of Science and Chair of the Biological Sciences Advisory and Tenure Promotion Committees.

Paul

In one other study his group demonstrated that a historical past of prior RNA virus evolution in multiple hosts can foster the emergence of these viruses in novel hosts . Infectious ailments are prevalent in Cambodia, a rustic that is struggling with poor infrastructure. Streptococcus pneumoniae causes essentially the most severe type of pneumonia and is now focused by the pneumococcal conjugate vaccine. Additionally, Turner’s staff has demonstrated that viruses endure evolutionary trade-offs across selective temperatures and across differing innate immune profiles of hosts.

  • Paul Turner is the Elihu Professor of Ecology and Evolutionary Biology at Yale University, and school member in Microbiology at Yale School of Medicine.
  • He additionally typically collaborates together with his graduate college students and postdoctoral fellows, crediting his students and mentees for his or her inspiration and assist over time.
  • With Lenski and a colleague, Turner used plasmids as fashions to check the theorized systematic trade-off between infectious and intergenerational modes of parasite transmission .
  • at Imperial College London, the place his sponsors include John Warner, Stephen Durham and Gideon Lack.

Turner’s research incessantly makes use of microbes as model techniques to test evolutionary and ecological theories. With Lenski and a colleague, Turner used plasmids as fashions to test the theorized systematic trade-off between infectious and intergenerational modes of parasite transmission . The researchers confirmed that infectious parasites cannot evolve to concurrently maximize horizontal and vertical transfers between hosts.

Novel Phage Remedy Strategy

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